Thiamethoxam is a neonicotinoid insecticide, which can selectively inhibit the nicotinic acetylcholin esterase receptor of the insect's central nervous system, thus cutting off the functioning of the insect's central nervous system, which causes its paralysis and death. As a seed treatment agent, thiamethoxam has five major advantages:

1. Higher activity

Thiamethoxam greatly increases the activity on contact toxicity and stomach toxicity against piercing and chewing insects. Its metabolic clothianidin inside the insect has a higher affinity for the acetylcholine receptor, enabling it to have a higher insecticidal activity.

2. Higher water solubility

Thiamethoxam is highly soluble in water; there is no impact on the absorption of wheat and utilization of thiamethoxam.

3. Low resistance

Its risk of cross-resistance to the brown plant hopper and cotton aphid is very low.

4. Enhancement of the stress resistance of crops to increase crop growth

Thiamethoxam has a unique advantage – the function of enhancement of growth of roots and seedlings. Research revealed that thiamethoxam can activate plant stress-tolerant protein. Meanwhile, it affects the plant in vivo auxin, cytokinin, gibberellin, abscisic acid, peroxidase, polyphenol oxidase and Mouse PAL, which makes the crop's stem and root strong, as well as increases the stress resistance of crops.

5. Long-lasting effect

Thiamethoxam has a strong foliar-conducting activity and good root systemicity, enabling it to be fully absorbed in a very short time. When it is applied to soil or seeds, thiamethoxam is absorbed quickly by roots or germinal seedlings. Thiamethoxam then goes upward into all the parts of the plant through the plant xylem; it stays for a long while in the plant body, degrades slowly and lasts longer. Meanwhile, the degradant clothianidin has a higher insecticidal activity.